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KMID : 0361620070420030305
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Journal of the Korean Orthopaedic Association
2007 Volume.42 No. 3 p.305 ~ p.309
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Smoking, Alcohol Intake and the Risk of Dupuytren’s Disease in Koreans
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Hahn Soo-Bong
Kang Ho-Jung
Lee Seung-Hwan
Kim Hong-Kyun
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Abstract
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Purpose : This study evaluated the relationship between Dupuytrens disease and smoking and alcohol intake.
Materials and Methods : Forty eight patients with Dupuytrens disease, who underwent a partial fasiectomy were examined retrospectively through a chart review and a telephone interview. The minimum follow-up period was 12 months. The relationship between Dupuytren’s disease and smoking and alcohol intake were analyzed using multivariate logistic regression with significance set at p＜0.05.
Results : Dupuytren’s disease requiring surgery in these patients was associated with heavy alcohol intake (odds ratio 2.91) and alcohol intake per week (odds ratio 1.22). The average smoking level was 24.7 pack-year for cases compared with 16.1 pack-year for controls (p＜0.05). The average alcohol intake was 3.0 units per week for the cases compared with 1.2 units per week for controls (p＜0.05). Smoking was not an independent risk factor but increased the risk when combined with heavy alcohol intake.
Conclusion : Heavy alcohol intake is an independent risk factor of Dupuytren’s disease in Korean. Smoking is not an independent risk factor but increases the risk when combined with heavy alcohol intake.
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KEYWORD
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Dupuytren, Smoking, Alcohol
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